RIP2 promotes FcγR-mediated reactive oxygen species production

Receptor-interacting protein 2 (RIP2) is a kinase that mediates signaling downstream of the bacterial peptidoglycan sensors NOD1 and NOD2. Genetic loss or pharmaceutical inhibition of RIP2 has been shown to be beneficial in multiple inflammatory disease models with the effects largely attributed to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Shehat, Michael G., Cardona, Omar A., Aranjuez, George F., Jewett, Mollie W., Tigno-Aranjuez, Justine T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2019
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664193/
https://ncbi.nlm.nih.gov/pubmed/31113864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007218
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