RIP2 promotes FcγR-mediated reactive oxygen species production

Receptor-interacting protein 2 (RIP2) is a kinase that mediates signaling downstream of the bacterial peptidoglycan sensors NOD1 and NOD2. Genetic loss or pharmaceutical inhibition of RIP2 has been shown to be beneficial in multiple inflammatory disease models with the effects largely attributed to...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Shehat, Michael G., Cardona, Omar A., Aranjuez, George F., Jewett, Mollie W., Tigno-Aranjuez, Justine T.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664193/
https://ncbi.nlm.nih.gov/pubmed/31113864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007218
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