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Chronic Ly49H Receptor Engagement in vivo Decreases NK Cell Response to Stimulation Through ITAM-Dependent and Independent Pathways Both in vitro and in vivo

Natural killer (NK) cells play an important role in the innate immune response. The summation of activation and inhibitory signals delivered through cell surface membrane receptors determines NK cell function. However, the continuous engagement of an activating receptor on NK cells appears to render...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Key, Phillip N., Germino, Joe, Yang, Liping, Piersma, Sytse J., Tripathy, Sandeep K.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664057/
https://ncbi.nlm.nih.gov/pubmed/31396217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01692
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