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Silibinin ameliorates hepatic lipid accumulation and oxidative stress in mice with non-alcoholic steatohepatitis by regulating CFLAR-JNK pathway

Non-alcoholic steatohepatitis (NASH) is a chronic metabolic syndrome and the CFLAR-JNK pathway can reverse the process of NASH. Although silibinin is used for the treatment of NASH in clinical, its effect on CFLAR-JNK pathway in NASH remains unclear. This study aimed to investigate the effect of sil...

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Bibliografiske detaljer
Udgivet i:Acta Pharm Sin B
Main Authors: Liu, Yayun, Xu, Wei, Zhai, Ting, You, Jiaojiao, Chen, Yong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664044/
https://ncbi.nlm.nih.gov/pubmed/31384535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.02.006
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