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Silibinin ameliorates hepatic lipid accumulation and oxidative stress in mice with non-alcoholic steatohepatitis by regulating CFLAR-JNK pathway

Non-alcoholic steatohepatitis (NASH) is a chronic metabolic syndrome and the CFLAR-JNK pathway can reverse the process of NASH. Although silibinin is used for the treatment of NASH in clinical, its effect on CFLAR-JNK pathway in NASH remains unclear. This study aimed to investigate the effect of sil...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Liu, Yayun, Xu, Wei, Zhai, Ting, You, Jiaojiao, Chen, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664044/
https://ncbi.nlm.nih.gov/pubmed/31384535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.02.006
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