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Uptake and efflux of FL118 and two FL118 derivatives in 3D cell model

Drug uptake and efflux are two of the critical factors required in order to be able to define drug efficacy. This study aims to investigate cytotoxicity and uptake mechanisms of two FL118 analogues (7-Q20 and val-FL118) in parallel with FL118 in three-dimensional multi-cellular spheroids model. The...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Zhou, Leilei, Weng, Qi, Zheng, Yixin, Zhou, Yuqin, Li, Qingyong, Li, Fengzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663949/
https://ncbi.nlm.nih.gov/pubmed/31309350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-019-00322-5
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