Safety and feasibility of estrogen receptor β targeted PhytoSERM formulation for menopausal symptoms: Phase 1b/2a randomized clinical trial

OBJECTIVE: PhytoSERM is a formulation of genistein, daidzein, and S-equol that has an 83-fold selective affinity for estrogen receptor-β (ERβ); and may enhance neuron function and estrogenic mechanisms in the brain without having peripheral estrogenic activity. METHODS: We conducted an overarching,...

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Bibliographic Details
Published in:Menopause
Main Authors: Schneider, Lon S., Hernandez, Gerson, Zhao, Liqin, Franke, Adrian A., Chen, Yu-Ling, Pawluczyk, Sonia, Mack, Wendy J., Brinton, Roberta D.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663614/
https://ncbi.nlm.nih.gov/pubmed/30889096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0000000000001325
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