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Retrospective Analysis of PhytoSERM for Management of Menopause-Associated Vasomotor Symptoms and Cognitive Decline: A Pilot Study on Pharmacogenomic Effects of Mitochondrial Haplogroup and APOE Genotype on Therapeutic Efficacy

OBJECTIVE: PhytoSERM is a selective estrogen receptor beta (ERβ) modulator comprised of three phytoestrogens: genistein, daidzein, and S-equol. The PhytoSERM formulation promotes estrogenic action in the brain while largely inactive or inhibitory in reproductive tissue. A Phase Ib/IIa clinical trial...

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Detalhes bibliográficos
Publicado no:Menopause
Main Authors: Wang, Yiwei, Hernandez, Gerson, Mack, Wendy J., Schneider, Lon S., Yin, Fei, Brinton, Roberta D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100617/
https://ncbi.nlm.nih.gov/pubmed/31567873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GME.0000000000001418
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