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Aptamer-field-effect transistors overcome Debye length limitations for small-molecule sensing

Detection of analytes with field-effect transistors bearing ligand-specific receptors is fundamentally limited by the shielding created by the electrical double layer (the “Debye length” limitation). We detected small molecules under physiological high ionic-strength conditions by modifying printed...

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Bibliographische Detailangaben
Veröffentlicht in:Science
Hauptverfasser: Nakatsuka, Nako, Yang, Kyung-Ae, Abendroth, John M., Cheung, Kevin, Xu, Xiaobin, Yang, Hongyan, Zhao, Chuanzhen, Zhu, Bowen, Rim, You Seung, Yang, Yang, Weiss, Paul S., Stojanović, Milan N., Andrews, Anne M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663484/
https://ncbi.nlm.nih.gov/pubmed/30190311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao6750
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