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Identifying disease-associated copy number variations by a doubly penalized regression model

Copy number variation (CNV) of DNA plays an important role in the development of many diseases. However, due to the irregularity and sparsity of the CNVs, studying the association between CNVs and a disease outcome or a trait can be challenging. Up to now, not many methods have been proposed in the...

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Библиографические подробности
Опубликовано в: :Biometrics
Главные авторы: Cheng, Yichen, Dai, James Y., Wang, Xiaoyu, Kooperberg, Charles
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663092/
https://ncbi.nlm.nih.gov/pubmed/29894562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12920
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