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m(6)A enhances the phase separation potential of mRNA

N(6)-methyladenosine (m(6)A) is the most prevalent modified nucleotide in mRNA(1,2), with ~25% of mRNAs containing at least one m(6)A. Methylation of mRNA to form m(6)A is required for diverse cellular and physiological processes(3). Although the presence of m(6)A in an mRNA can affect its fate in d...

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Publicado en:Nature
Autores principales: Ries, Ryan J., Zaccara, Sara, Klein, Pierre, Olarerin-George, Anthony, Namkoong, Sim, Pickering, Brian F., Patil, Deepak P., Kwak, Hojoong, Lee, Jun Hee, Jaffrey, Samie R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662915/
https://ncbi.nlm.nih.gov/pubmed/31292544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1374-1
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