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m(6)A enhances the phase separation potential of mRNA

N(6)-methyladenosine (m(6)A) is the most prevalent modified nucleotide in mRNA(1,2), with ~25% of mRNAs containing at least one m(6)A. Methylation of mRNA to form m(6)A is required for diverse cellular and physiological processes(3). Although the presence of m(6)A in an mRNA can affect its fate in d...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Ries, Ryan J., Zaccara, Sara, Klein, Pierre, Olarerin-George, Anthony, Namkoong, Sim, Pickering, Brian F., Patil, Deepak P., Kwak, Hojoong, Lee, Jun Hee, Jaffrey, Samie R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662915/
https://ncbi.nlm.nih.gov/pubmed/31292544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1374-1
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