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Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis

INTRODUCTION: Many studies have shown that COPD is associated with apoptosis of bronchial or alveolar epithelial cells. Alveolar type II epithelial cells (AECII) play an important role in the pathogenetic process. Cigarette smoke extract (CSE) can induce apoptosis of AECII. The Sonic hedgehog (Shh)...

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Bibliographische Detailangaben
Veröffentlicht in:Tob Induc Dis
Hauptverfasser: Li, Jinhua, Zong, Dandan, Chen, Yan, Chen, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Publishing on behalf of the International Society for the Prevention of Tobacco Induced Diseases (ISPTID) 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662799/
https://ncbi.nlm.nih.gov/pubmed/31516492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18332/tid/109753
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