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A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids
Steroidal C19-hydroxylation is pivotal to the synthesis of naturally occurring bioactive C19-OH steroids and 19-norsteroidal pharmaceuticals. However, realizing this transformation is proved to be challenging through either chemical or biological synthesis. Herein, we report a highly efficient metho...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662754/ https://ncbi.nlm.nih.gov/pubmed/31358750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11344-0 |
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