A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids

Steroidal C19-hydroxylation is pivotal to the synthesis of naturally occurring bioactive C19-OH steroids and 19-norsteroidal pharmaceuticals. However, realizing this transformation is proved to be challenging through either chemical or biological synthesis. Herein, we report a highly efficient metho...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Wang, Junlin, Zhang, Yanan, Liu, Huanhuan, Shang, Yong, Zhou, Linjun, Wei, Penglin, Yin, Wen-Bing, Deng, Zixin, Qu, Xudong, Zhou, Qianghui
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662754/
https://ncbi.nlm.nih.gov/pubmed/31358750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11344-0
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky