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Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD

YAP (also known as YAP1 or YAP65) is a transcriptional coactivator that interacts with a number of transcription factors including RUNX and TEAD and plays a pivotal role in controlling cell growth. YAP is classified as a proto-oncogene. However, the mechanism by which activated YAP induces cancerous...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Nishimoto, Masazumi, Uranishi, Kousuke, Asaka, Masamitsu N., Suzuki, Ayumu, Mizuno, Yosuke, Hirasaki, Masataka, Okuda, Akihiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662713/
https://ncbi.nlm.nih.gov/pubmed/31358774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47301-6
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