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Transformation of normal cells by aberrant activation of YAP via cMyc with TEAD
YAP (also known as YAP1 or YAP65) is a transcriptional coactivator that interacts with a number of transcription factors including RUNX and TEAD and plays a pivotal role in controlling cell growth. YAP is classified as a proto-oncogene. However, the mechanism by which activated YAP induces cancerous...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662713/ https://ncbi.nlm.nih.gov/pubmed/31358774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47301-6 |
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