A genome-wide scan of cleft lip triads identifies parent-of-origin interaction effects between ANK3 and maternal smoking, and between ARHGEF10 and alcohol consumption

Background: Although both genetic and environmental factors have been reported to influence the risk of isolated cleft lip with or without cleft palate (CL/P), the exact mechanisms behind CL/P are still largely unaccounted for. We recently developed new methods to identify parent-of-origin (PoO) int...

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Publicado en:F1000Res
Autores principales: Haaland, Øystein Ariansen, Romanowska, Julia, Gjerdevik, Miriam, Lie, Rolv Terje, Gjessing, Håkon Kristian, Jugessur, Astanand
Formato: Artigo
Lenguaje:Inglês
Publicado: F1000 Research Limited 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662680/
https://ncbi.nlm.nih.gov/pubmed/31372216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.19571.2
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