A Genome-Wide Search for Gene-Environment Effects in Isolated Cleft Lip with or without Cleft Palate Triads Points to an Interaction between Maternal Periconceptional Vitamin Use and Variants in ESRRG

Background: It is widely accepted that cleft lip with or without cleft palate (CL/P) results from the complex interplay between multiple genetic and environmental factors. However, a robust investigation of these gene-environment (GxE) interactions at a genome-wide level is still lacking for isolate...

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Veröffentlicht in:Front Genet
Hauptverfasser: Haaland, Øystein A., Lie, Rolv T., Romanowska, Julia, Gjerdevik, Miriam, Gjessing, Håkon K., Jugessur, Astanand
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834486/
https://ncbi.nlm.nih.gov/pubmed/29535761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00060
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