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Reversal of ultrasonic vocalization deficits in a mouse model of Fragile X Syndrome with minocycline treatment or genetic reduction of MMP-9

Fragile X Syndrome (FXS) is a leading genetic cause of autism and intellectual disabilities. The Fmr1 knockout (KO) mouse is a commonly studied pre-clinical model of FXS. Adult male Fmr1 KO mice produce fewer ultrasonic vocalizations (USVs) during mating, suggestive of abnormal social communication....

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Bibliografski detalji
Izdano u:Behav Brain Res
Glavni autori: Toledo, Maximiliano A., Wen, Teresa H., Binder, Devin K., Ethell, Iryna M., Razak, Khaleel A.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662633/
https://ncbi.nlm.nih.gov/pubmed/31271818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112068
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