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Succinylation Is a Gain-of-Function Modification in Human Lens αB-Crystallin
Acylation of lysine residues is a common post-translational modification of cellular proteins. Here, we show that lysine succinylation, a type of acylation, occurs in human lens proteins. All of the major crystallins exhibited N(ε)-succinyllysine (SuccK) residues. Quantification of SuccK in human le...
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| Publié dans: | Biochemistry |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662615/ https://ncbi.nlm.nih.gov/pubmed/30758948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01053 |
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