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Characteristics of Single Pivotal Trials Supporting Regulatory Approvals of Novel Non‐orphan, Non‐oncology Drugs in the European Union and United States from 2012−2016

For regulatory approval of a new medicine, the gold standard for demonstration of efficacy has traditionally been a minimum of two positive, adequate, and well‐controlled clinical trials. Nevertheless, drugs to treat cancer and rare diseases are usually approved based on a single and often uncontrol...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Morant, Anne Vinther, Jagalski, Vivien, Vestergaard, Henrik Tang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662549/
https://ncbi.nlm.nih.gov/pubmed/30681284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12617
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