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Predictors of orphan drug approval in the European Union

OBJECTIVE: To encourage the development of drugs for rare diseases, orphan drug legislation has been introduced in the USA (1983) and in the EU (2000). Recent literature discusses factors that may influence the development of new orphan medicinal products in the EU. This study aims to identify predi...

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Main Authors: Heemstra, Harald E., de Vrueh, Remco L., van Weely, Sonja, Büller, Hans A., Leufkens, Hubert G. M.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668549/
https://ncbi.nlm.nih.gov/pubmed/18210097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-007-0454-6
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