Evidence of Augmented Intrarenal Angiotensinogen Associated With Glomerular Swelling in Gestational Hypertension and Preeclampsia: Clinical Implications

BACKGROUND: AGT (angiotensinogen) synthesis occurs in renal proximal tubular epithelial cells, independent from systemic AGT, as a component of the intrarenal renin–angiotensin system. We investigated urinary AGT, as a biomarker for renin–angiotensin system activation, and electrolyte concentrations...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Mistry, Hiten D., Kurlak, Lesia O., Gardner, David S., Torffvit, Ole, Hansen, Alastair, Broughton Pipkin, Fiona, Strevens, Helena
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662362/
https://ncbi.nlm.nih.gov/pubmed/31237175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012611
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