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Augmented intrarenal and urinary angiotensinogen in hypertension and chronic kidney disease

Activated intrarenal renin–angiotensin system plays a cardinal role in the pathogenesis of hypertension and chronic kidney disease. Angiotensinogen is the only known substrate for renin, which is the rate-limiting enzyme of the renin–angiotensin system. Because the levels of angiotensinogen are clos...

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Detalhes bibliográficos
Main Authors: Kobori, Hiroyuki, Urushihara, Maki
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515740/
https://ncbi.nlm.nih.gov/pubmed/22918624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1143-6
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