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Ethanol stimulates endoplasmic reticulum inositol triphosphate and sigma receptors to promote withdrawal-associated loss of neuron specific nuclear protein/Fox-3

BACKGROUND: Prior studies demonstrate that ethanol exposure induces the release of intracellular calcium (CA(2+)) in modulation of γ-Aminobutyric acid (GABA)-ergic tone and produces concomitant alterations in sigma (σ)-1 protein expression that may contribute to the development ethanol dependence. H...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Reynolds, Anna R., Saunders, Meredith A., Prendergast, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662182/
https://ncbi.nlm.nih.gov/pubmed/27177604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.13097
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