CRISPR/Cas9 Delivery Mediated with Hydroxyl‐Rich Nanosystems for Gene Editing in Aorta

A CRISPR/Cas9 system has emerged as a powerful tool for gene editing to treat genetic mutation related diseases. Due to the complete endothelial barrier, effective delivery of the CRISPR/Cas9 system to vasculatures remains a challenge for in vivo gene editing of genetic vascular diseases especially...

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Publicado en:Adv Sci (Weinh)
Autores principales: Zhang, Xiaoping, Xu, Chen, Gao, Shijuan, Li, Ping, Kong, Yu, Li, Tiantian, Li, Yulin, Xu, Fu‐Jian, Du, Jie
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Full Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662060/
https://ncbi.nlm.nih.gov/pubmed/31380173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900386
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