Assessment of lipophilicity of newly synthesized celecoxib analogues using reversed-phase HPLC

BACKGROUND: Lipophilicity is a physicochemical property of an essential importance in medicinal chemistry; therefore, fast and reliable measurement of lipophilicity will affect greatly the drug discovery process. RESULTS: A series of N-benzenesulfonamide-1H-pyrazoles, oximes and hydrazones as celeco...

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Detalhes bibliográficos
Publicado no:BMC Chem
Main Authors: Elmansi, Heba, Nasr, Jenny Jeehan, Rageh, Azza H., El-Awady, Mohamed I., Hassan, Ghada S., Abdel-Aziz, Hatem A., Belal, Fathalla
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661952/
https://ncbi.nlm.nih.gov/pubmed/31384831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-019-0607-6
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