Rapid micellar HPLC analysis of loratadine and its major metabolite desloratadine in nano-concentration range using monolithic column and fluorometric detection: application to pharmaceuticals and biological fluids

BACKGROUND: Loratadine is a commonly used selective non-sedating antihistaminic drug. Desloratadine is the active metabolite of loratadine and, in addition, a potential impurity in loratadine bulk powder stated by the United States Pharmacopeia as a related substance of loratadine. Published methods...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Chem Cent J
Autori principali: Belal, Fathalla, Abd El-Razeq, Sawsan, El-Awady, Mohamed, Zayed, Sahar, Barghash, Sona
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395507/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-016-0225-5
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