Drug Development: A Helical Polypeptide‐Based Potassium Ionophore Induces Endoplasmic Reticulum Stress‐Mediated Apoptosis by Perturbing Ion Homeostasis (Adv. Sci. 14/2019)

In article number of 1801995, Chae‐Ok Yun, Yeu‐Chun Kim, and co‐workers develop helical polypeptide‐based potassium ionophores that can drive out potassium ions from the cytosol. The perturbed potassium homeostasis strongly inflicts endoplasmic reticulum stress to cells and then creates severe oxida...

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Pubblicato in:Adv Sci (Weinh)
Autori principali: Lee, DaeYong, Lee, Soo‐Hwan, Noh, Ilkoo, Oh, Eonju, Ryu, Hyunil, Ha, JongHoon, Jeong, SeongDong, Yoo, Jisang, Jeon, Tae‐Joon, Yun, Chae‐Ok, Kim, Yeu‐Chun
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661932/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201970087
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