Drug Development: A Helical Polypeptide‐Based Potassium Ionophore Induces Endoplasmic Reticulum Stress‐Mediated Apoptosis by Perturbing Ion Homeostasis (Adv. Sci. 14/2019)

In article number of 1801995, Chae‐Ok Yun, Yeu‐Chun Kim, and co‐workers develop helical polypeptide‐based potassium ionophores that can drive out potassium ions from the cytosol. The perturbed potassium homeostasis strongly inflicts endoplasmic reticulum stress to cells and then creates severe oxida...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Lee, DaeYong, Lee, Soo‐Hwan, Noh, Ilkoo, Oh, Eonju, Ryu, Hyunil, Ha, JongHoon, Jeong, SeongDong, Yoo, Jisang, Jeon, Tae‐Joon, Yun, Chae‐Ok, Kim, Yeu‐Chun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661932/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201970087
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