Polygenic prediction of weight and obesity trajectories from birth to adulthood

Severe obesity is a rapidly growing global health threat. Although often attributed to unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and highly polygenic – the majority of inherited susceptibility is related to the cumulative impact of many common DNA variant...

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Publicado no:Cell
Main Authors: Khera, Amit V., Chaffin, Mark, Wade, Kaitlin H., Zahid, Sohail, Brancale, Joseph, Xia, Rui, Distefano, Marina, Senol-Cosar, Ozlem, Haas, Mary E., Bick, Alexander, Aragam, Krishna G., Lander, Eric S., Smith, George Davey, Mason-Suares, Heather, Fornage, Myriam, Lebo, Matthew, Timpson, Nicholas J., Kaplan, Lee M., Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661115/
https://ncbi.nlm.nih.gov/pubmed/31002795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.03.028
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