Genipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer

BACKGROUND: Genipin is a compound derived from gardenia fruit extract. Although Genipin has anti-tumor effects in various cancers, its effect and mechanism in gastric cancer remain unclear. Here, we investigated the relationship between the anticancer effect of Genipin and signal transducer and acti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Jo, Min Jee, Jeong, Soyeon, Yun, Hye Kyeong, Kim, Dae Yeong, Kim, Bo Ram, Kim, Jung Lim, Na, Yoo Jin, Park, Seong Hye, Jeong, Yoon A., Kim, Bu Gyeom, Ashktorab, Hassan, Smoot, Duane T., Heo, Jun Young, Han, Jeongsu, Lee, Dae-Hee, Oh, Sang Cheul
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661087/
https://ncbi.nlm.nih.gov/pubmed/31351462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5957-x
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