Genipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer

BACKGROUND: Genipin is a compound derived from gardenia fruit extract. Although Genipin has anti-tumor effects in various cancers, its effect and mechanism in gastric cancer remain unclear. Here, we investigated the relationship between the anticancer effect of Genipin and signal transducer and acti...

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Vydáno v:BMC Cancer
Hlavní autoři: Jo, Min Jee, Jeong, Soyeon, Yun, Hye Kyeong, Kim, Dae Yeong, Kim, Bo Ram, Kim, Jung Lim, Na, Yoo Jin, Park, Seong Hye, Jeong, Yoon A., Kim, Bu Gyeom, Ashktorab, Hassan, Smoot, Duane T., Heo, Jun Young, Han, Jeongsu, Lee, Dae-Hee, Oh, Sang Cheul
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661087/
https://ncbi.nlm.nih.gov/pubmed/31351462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5957-x
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