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Helical side chain chemistry of a peptoid-based SP-C analogue: balancing structural rigidity and biomimicry

Surfactant protein C (SP-C) is an important constituent of lung surfactant (LS) and, along with SP-B, is included in exogenous surfactant replacement therapies for treating respiratory distress syndrome (RDS). SP-C’s biophysical activity depends upon the presence of a rigid C-terminal helix, of whic...

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Detaylı Bibliyografya
Yayımlandı:Biopolymers
Asıl Yazarlar: Brown, Nathan J., Lin, Jennifer S., Barron, Annelise E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661009/
https://ncbi.nlm.nih.gov/pubmed/30972750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23277
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