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Helical side chain chemistry of a peptoid-based SP-C analogue: balancing structural rigidity and biomimicry
Surfactant protein C (SP-C) is an important constituent of lung surfactant (LS) and, along with SP-B, is included in exogenous surfactant replacement therapies for treating respiratory distress syndrome (RDS). SP-C’s biophysical activity depends upon the presence of a rigid C-terminal helix, of whic...
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| Udgivet i: | Biopolymers |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6661009/ https://ncbi.nlm.nih.gov/pubmed/30972750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23277 |
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