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pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis
Axonal degeneration is central to clinical disability and disease progression in multiple sclerosis (MS). Myeloid cells such as brain-resident microglia and blood-borne monocytes are thought to be critically involved in this degenerative process. However, the exact underlying mechanisms have still n...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6660731/ https://ncbi.nlm.nih.gov/pubmed/31213545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901283116 |
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