Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury

Traumatic primary spinal cord injury (SCI) results in paralysis below the level of injury and is associated with infiltration of hematogenous innate immune cells into the injured cord. Methylprednisolone has been applied to reduce inflammation following SCI, yet was discontinued due to an unfavorabl...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Park, Jonghyuck, Zhang, Yining, Saito, Eiji, Gurczynski, Steve J., Moore, Bethany B., Cummings, Brian J., Anderson, Aileen J., Shea, Lonnie D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660718/
https://ncbi.nlm.nih.gov/pubmed/31285339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820276116
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