Local Immunomodulation with Anti-inflammatory Cytokine-Encoding Lentivirus Enhances Functional Recovery after Spinal Cord Injury

Trauma to the spinal cord and associated secondary inflammation can lead to permanent loss of sensory and motor function below the injury level, with the resulting environment serving as a barrier that limits regeneration. In this study, we investigate the localized expression of anti-inflammatory c...

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Pubblicato in:Mol Ther
Autori principali: Park, Jonghyuck, Decker, Joseph T., Margul, Daniel J., Smith, Dominique R., Cummings, Brian J., Anderson, Aileen J., Shea, Lonnie D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6037204/
https://ncbi.nlm.nih.gov/pubmed/29778523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.022
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