Systemic TLR2 tolerance enhances central nervous system remyelination

BACKGROUND: Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease characterized by both inflammatory demyelination and impaired remyelination. Studies indicate that Toll-like receptor 2 (TLR2) signaling contributes to both the inflammatory component and the defective remyelina...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Wasko, Nicholas J., Kulak, Meghan Horne, Paul, Debayon, Nicaise, Alexandra M., Yeung, Stephen T., Nichols, Frank C., Khanna, Kamal M., Crocker, Stephen, Pachter, Joel S., Clark, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660683/
https://ncbi.nlm.nih.gov/pubmed/31351476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1540-2
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