HMGB1 and Caveolin-1 related to RPE cell senescence in age-related macular degeneration

Accumulation of lipofuscin in the retinal pigment epithelium (RPE) is considered a major cause of RPE dysfunction and senescence in age-related macular degeneration (AMD), and N-retinylidene-N-retinylethanolamine (A2E) is the main fluorophore identified in lipofuscin from aged human eyes. Here, huma...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Sun, Shuo, Cai, Bincui, Li, Yao, Su, Wenqi, Zhao, Xuzheng, Gong, Boteng, Li, Zhiqing, Zhang, Xiaomin, Wu, Yalin, Chen, Chao, Tsang, Stephen H., Yang, Jin, Li, Xiaorong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660032/
https://ncbi.nlm.nih.gov/pubmed/31284269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102039
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