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Heterologous prime-boost immunization with vesiculovirus-based vectors expressing HBV Core antigen induces CD8(+) T cell responses in naïve and persistently infected mice and protects from challenge
Chronic hepatitis B virus (HBV) infections cause more than 800,000 deaths per year and currently approved treatments do not cure the disease. Because a hallmark of acute infection resolution is the presence of functional CD8(+) T cells to the virus, activation of the immune system with therapeutic v...
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| Publicado no: | Antiviral Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6660017/ https://ncbi.nlm.nih.gov/pubmed/31153968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.05.014 |
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