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EMERGING DRUG PROFILE: Enhancer of Zeste Homolog 2 (EZH2) Inhibitors

Dysregulation of the histone methyltransferase EZH2 plays a critical role in the development of a variety of malignancies including B-cell lymphomas. As a result, a series of small molecule inhibitors of EZH2 have been developed and studied in the pre-clinical setting. Three EZH2 inhibitors: tazemet...

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Detalhes bibliográficos
Publicado no:Leuk Lymphoma
Main Authors: Gulati, Nitya, Beguelin, Wendy, Giulino-Roth, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659997/
https://ncbi.nlm.nih.gov/pubmed/29473431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2018.1430795
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