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BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus

Pruritus is an unexpected symptom observed in cholestasis and its mechanism is still unclear. Here, we show that bovine adrenal medulla (BAM) 8–22, an endogenous itch-inducing peptide, could be involved in cholestatic pruritus. It was found that bile duct ligation (BDL) mice, an obstructive cholesta...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Sanjel, Babina, Maeng, Han-Joo, Shim, Won-Sik
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659683/
https://ncbi.nlm.nih.gov/pubmed/31350433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47267-5
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