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Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1
Neuropilin-1 (Nrp-1) is a marker for murine CD4(+)FoxP3(+) regulatory T (Treg) cells, a subset of human CD4(+) Treg cells, and a population of CD8(+) T cells infiltrating certain solid tumours. However, whether Nrp-1 regulates tumour-specific CD8 T-cell responses is still unclear. Here we show that...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6659631/ https://ncbi.nlm.nih.gov/pubmed/31350404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11280-z |
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