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Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity

Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs, as VPA-induced hepatotoxicity is one of the most severe adverse reaction that can lead to death. The objective of this study was to gain an understanding of dysregulated lipid metabolism in mechanism of hepatotoxicity. Non...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Xu, Shansen, Chen, Yanan, Ma, Yiyi, Liu, Ting, Zhao, Mingming, Wang, Zhanyou, Zhao, Limei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659130/
https://ncbi.nlm.nih.gov/pubmed/31379584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00819
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