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Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity

Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs, as VPA-induced hepatotoxicity is one of the most severe adverse reaction that can lead to death. The objective of this study was to gain an understanding of dysregulated lipid metabolism in mechanism of hepatotoxicity. Non...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Xu, Shansen, Chen, Yanan, Ma, Yiyi, Liu, Ting, Zhao, Mingming, Wang, Zhanyou, Zhao, Limei
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659130/
https://ncbi.nlm.nih.gov/pubmed/31379584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00819
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