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Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity

Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs, as VPA-induced hepatotoxicity is one of the most severe adverse reaction that can lead to death. The objective of this study was to gain an understanding of dysregulated lipid metabolism in mechanism of hepatotoxicity. Non...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xu, Shansen, Chen, Yanan, Ma, Yiyi, Liu, Ting, Zhao, Mingming, Wang, Zhanyou, Zhao, Limei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659130/
https://ncbi.nlm.nih.gov/pubmed/31379584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00819
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