Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults

OBJECTIVE: To assess cross-sectional associations of neurofibrillary tangles, measured by tau-PET, with cognitive performance in cognitively unimpaired (CU) adults. METHODS: Tau- and amyloid-PET were performed in 579 CU participants aged 50–98 from the population-based Mayo Clinic Study of Aging. As...

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Udgivet i:Neurology
Main Authors: Lowe, Val J., Bruinsma, Tyler J., Wiste, Heather J., Min, Hoon-Ki, Weigand, Stephen D., Fang, Ping, Senjem, Matthew L., Therneau, Terry M., Boeve, Bradley F., Josephs, Keith A., Pandey, Mukesh K., Murray, Melissa E., Kantarci, Kejal, Jones, David T., Vemuri, Prashanthi, Graff-Radford, Jonathan, Schwarz, Christopher G., Machulda, Mary M., Mielke, Michelle M., Roberts, Rosebud O., Knopman, David S., Petersen, Ronald C., Jack, Clifford R.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659005/
https://ncbi.nlm.nih.gov/pubmed/31147421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000007728
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