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Reactive Oxygen Species Production Is a Major Factor Directing the Postantibiotic Effect of Fluoroquinolones in Streptococcus pneumoniae

We studied the molecular mechanisms involved in the postantibiotic effect of the fluoroquinolones levofloxacin and moxifloxacin in Streptococcus pneumoniae. Wild-type strain R6 had postantibiotic effects of 2.05 ± 0.10 h (mean ± standard deviation [SD]) and 3.23 ± 0.45 h at 2.5× and 10× MIC of levof...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: García, M. T., Valenzuela, M. V., Ferrándiz, M. J., de la Campa, A. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658797/
https://ncbi.nlm.nih.gov/pubmed/31160286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00737-19
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