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The Warburg effect: persistence of stem-cell metabolism in cancers as a failure of differentiation
BACKGROUND: Two recent observations regarding the Warburg effect are that (i) the metabolism of stem cells is constitutive (aerobic) glycolysis while normal cellular differentiation involves a transition to oxidative phosphorylation and (ii) the degree of glucose uptake of a malignancy as imaged by...
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| Publicat a: | Ann Oncol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6658717/ https://ncbi.nlm.nih.gov/pubmed/29045536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdx645 |
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