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Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons

Directed differentiation of human pluripotent stem cells (hPSCs) has enabled the generation of specific neuronal subtypes that approximate the intended primary mammalian cells on both the RNA and protein levels. These cells offer unique opportunities, including insights into mechanistic understandin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Moakley, Daniel, Koh, Joan, Pereira, Joao D., DuBreuil, Daniel M., Devlin, Anna-Claire, Berezovski, Eugene, Zhu, Kevin, Wainger, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658502/
https://ncbi.nlm.nih.gov/pubmed/31346219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47203-7
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